Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Path: utzoo!utgpu!water!watmath!clyde!rutgers!ames!hc!beta!dd From: dd@beta.UUCP Newsgroups: sci.med,sci.bio Subject: Re: Dating age of humans Message-ID: <9516@beta.UUCP> Date: Mon, 31-Aug-87 01:29:11 EDT Article-I.D.: beta.9516 Posted: Mon Aug 31 01:29:11 1987 Date-Received: Tue, 1-Sep-87 01:07:56 EDT References: <26333@sun.uucp> <1960@kitty.UUCP> <3836@cit-vax.Caltech.Edu> Organization: Los Alamos Natl Lab, Los Alamos, N.M. Lines: 13 Keywords: Ageing Human Carbon Xref: utgpu sci.med:2722 sci.bio:569 Summary: Turnover times; DNA not permanent In article <3836@cit-vax.Caltech.Edu>, palmer@tybalt.caltech.edu (David Palmer) writes: > Since neurons do not reproduce (much) after birth, the DNA does not > change (does it?) so the same carbon atoms remain in the DNA as at birth. Nope. DNA is repaired even if the neuron does not divide. Thus the turn- over time, while long (I don't know the exact number, but I'd bet it's well under a year) is finite. If I remember correctly, the only compounds which are not turned over are the collagen-containing tendons and ligaments. I suspect the latest version of Principles of Biochemistry (White et al.) will have the details. dan davison/theoretical biology/t-10 ms k710/Los Alamos National Lab/Los Alamos, NM 87545. "I'm a doctor, not an elevator" Dr. McCoy