Path: utzoo!utgpu!water!watmath!uunet!ig!daemon From: BIORELAY@BIO.CAM.AC.UK Newsgroups: bionet.molbio.seqnet Subject: SEQNET Bulletin RELAY ONLY: reply to SEQNET@UK.AC.CAM.BIO Message-ID: <6570@ig.ig.com> Date: 6 Jun 88 10:08:06 GMT Sender: daemon@presto.ig.com Lines: 243 From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: MJB1@UK.AC.CAM.PHX 6-JUN-1988 09:32 To: SEQNET Subj: Date: Mon, 06 Jun 88 09:31:31 BST From: MJB1@UK.AC.CAM.PHX To: seqnet@UK.AC.CAM.BIO Message-ID: <9EA04E19F035BC60@UK.AC.CAM.PHX> (Message number 9) Accepted: 09:26:01 06 Jun 88 Submitted: 15:56:10 01 Jun 88 IPMessageId: -unspecified- From: HAZLEDINE@EARN.EMBL To: mjb1@UK.AC.CAM.PHX Subject: File server announcement for SEQNET Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 5632; Wed, 01 Jun 88 14:57:57 BS Received: from EMBL(HAZLEDIN) by UKACRL (Mailer X1.25) id 5624; Wed, 01 Jun 88 14:57:56 BS Organisation: European Molecular Biology Laboratory Postal-address: Meyerhofstrasse 1, 6900 Heidelberg, W. Germany Phone: +49 (6221) 387-0 [switchboard] Martin, Would you post this announcement about our file server upgrade on SEQNET please. (It's finally accessible from JANET!) Thanks, Dave. // EMBL Network File Server ------------------------ We are pleased to be able to announce a major upgrade to the EMBL file server. The server now accepts STANDARD ELECTRONIC MAIL, sent either over BITNET/EARN or FROM ANY OTHER NETWORK WHICH HAS A GATEWAY INTO BITNET/EARN. This means, to take just two examples, that users in the UK connected to JANET and users in the USA connected to ARPANET can now use the file server. You should send mail to the BITNET/EARN address NETSERV@EMBL; it should be formatted with one file server command per line. The most important command, to get you started, is HELP. If the file server receives this command, it will return a help file to you, explaining in some detail what you can do with the server and how to use it. Please note that the operating system command you use to send mail to a BITNET/EARN address, and the way in which you format the address NETSERV@EMBL, will depend both on the computer you are using and on the network to which it is connected. If you don't already know how to send mail to a BITNET/EARN address, we suggest that you contact your local computer service; if all else fails, contact the Data Library and we will do our best to help. For example, suppose you are using a VAX/VMS system which is a BITNET/EARN node running JNET software. In this case you would use the VMS MAIL command to send mail to the server. If you wanted to send a HELP command, your session on the VAX would look like this (user input in lowercase): $ MAIL MAIL> send To: jnet%"netserv@embl" Subj: help If the command you use to send mail allows you to specify a "subject", as in the above example, then please note that anything you specify as the "subject" will be treated as a file server command. Those of you who have already used the server, by sending interactive messages over BITNET/EARN, should note that this access method is still available. However, it offers no advantages over standard electronic mail and we would recommend that you switch to the latter. We would like to emphasise that you can use the file server to download sequences added to the EMBL database since the current release was distributed, in addition to the sequences in the current release itself. We are well aware that the file server is not (yet!) perfect, and are planning several enhancements. The most important ones are to give users direct access to sequences by accession number as well as by entry name, and to make index files available which cover just those sequences added to the database since the current release was distributed. (Such index files would be much smaller than the current ones, which cover all sequences in the database, and would thus be sent much more quickly over computer networks.) We hope to make progress on the question of direct access by accession number in the not too distant future, and would like to draw your attention to the fact that one of the index files (the catalogue of one-line entry descriptions) is already available for new sequences only. The file DATALIB:NEWENTS.TXT contains brief descriptions, entry names and sequence lengths for all those sequences added to the database since the current release was distributed. Like all of the other index files, it is updated daily to include all sequences newly added to the database. If you have any technical problems in accessing the file server then please mail to POSTMASTER@EMBL.EARN. If you have any general comments about the file server (or any other aspect of our services) then please send them to us; we want to tailor our services to meet your requirements, and the more feedback we get the better. We cannot undertake to respond personally to all comments, but you can be sure that we want to know what you think! EMBL Data Library Postfach 10.2209 D-6900 Heidelberg West Germany Telephone : +49-6221-387258 Email (general enquiries): DATALIB@EMBL.EARN Email (data submissions) : DATASUBS@EMBL.EARN From: BIO::BIONET 6-JUN-1988 09:44 To: SEQNET Subj: From: BIO::JCJB 1-JUN-1988 15:12 To: BIONET,JCJB Subj: PLEASE put this in the bulletin for EDL (again). UNIVERSITY OF CAMBRIDGE DEPARTMENT OF BIOCHEMISTRY POSTDOCTORAL RESEARCH ASSOCIATE EUKARYOTIC GENE EXPRESSION/PROTEIN-DNA INTERACTIONS Applications are invited for a three year postdoctoral position funded by the SERC Molecular Recognition Initiative to study yeast gene regulatory proteins. The work will use biochemical/molecular biological and NMR spectroscopic techniques to study the structure and function of these proteins. Applicants with experience in biochemistry/molecular biology would be very welcome, but candidates with other relevant backgrounds are encouraged to apply. The post is available (starting date negotiable) at a starting salary within the range 9,305 -13,675 pounds (according to age and experience). Applicants should apply before 31st June, sending a full C.V. naming two academic referees, to Dr. E.D. Laue, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, U.K., (telephone Cambridge 333677) from whom further details may be obtained. UNIVERSITY OF CAMBRIDGE DEPARTMENT OF BIOCHEMISTRY WITH MEIKO LTD. POSTDOCTORAL RESEARCH ASSOCIATE PARALLEL PROCESSING/PROTEIN STRUCTURE DETERMINATION Applications are invited for a three year postdoctoral position funded jointly by the SERC and Meiko Ltd. to work on the development of software for NMR data processing, including the Maximum Entropy Method (MEM), and protein structure determination. The software will be implemented on a Meiko Computing Surface, a parallel processor based on the Inmos Transputer. The successful applicant will collaborate with workers at Meiko Ltd. in Bristol and will be based in Cambridge. Applicants with experience in parallel computing or structure determination using NMR spectroscopy/X-ray diffraction would be particularly welcome. However, candidates with other relevant backgrounds are encouraged to apply. The post is available (starting date negotiable) at a starting salary within the range 9,305 - 13,675 pounds (according to age and experience). Applicants should apply before 31st June, sending a full C.V. and naming two academic referees, to Dr. E.D. Laue, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, U.K., (telephone Cambridge 333677) from whom further details may be obtained. UNIVERSITY OF CAMBRIDGE DEPARTMENTS OF CHEMISTRY AND BIOCHEMISTRY RESEARCH STUDENTSHIP IN NMR SPECTROSCOPY/PROTEIN STRUCTURE DETERMINATION Applications are invited for a 3 year Ph.D. studentship available from October 1988 and funded by the SERC for work on the development of NMR spectroscopic methods for protein structure determination. Applicants should have, or expect to obtain, a first or upper second class honours degree in Chemistry or Physics. Further information may be obtained from either Dr. J. Keeler (Department of Chemistry; Tel: Cambridge 336428) or Dr. E.D. Laue (Department of Biochemistry; Tel: Cambridge 333677). Applicants should send a full Curriculum Vitae and the names and addresses of two academic referees, as soon as possible, to either of the above.