Path: utzoo!utgpu!water!watmath!clyde!att!osu-cis!tut.cis.ohio-state.edu!mailrus!ncar!boulder!eddy
From: eddy@boulder.Colorado.EDU (Sean Eddy)
Newsgroups: sci.bio
Subject: Re: Chromatin Packing
Keywords: Chromatin
Message-ID: <3006@boulder.Colorado.EDU>
Date: 27 Aug 88 23:59:54 GMT
References: <707@dukempd.UUCP>
Sender: news@boulder.Colorado.EDU
Reply-To: eddy@boulder.Colorado.EDU (Sean Eddy)
Organization: University of Colorado, Boulder
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In article <707@dukempd.UUCP> crown@dukempd.UUCP (Rick Crownover) writes:
>                  In reading "The Cell" by Alberts et. al.  I ran across an
>'open question' about chromatin packing (ch. 8  pp 389).  I have
>a naive experimental approach to this question for discussion...
>but don't want to flog a dead horse.  The book is a couple of years
>old now; so, does anyone know whether this question has been 
>resolved in the meantime?  Thanks,  Rick

Resolved, in favor of the drawing to the right (nucleosome hockey-pucks
stacked on end rather than on their sides). Experimental technique
involved X-ray diffraction of chromatin fibers. The two models for
packing predicted different and distinguishable sets of reflections
(which I don't understand anyway). I can look up a reference if you
want. What was your experiment??

- Sean Eddy
- Molecular/Cellular/Developmental Biology; U. of Colorado at Boulder
- eddy@boulder.colorado.EDU		!{hao,nbires}!boulder!eddy	
-
- "Truth emerges more readily from error than from confusion."
-                       - Francis Bacon