Xref: utzoo sci.bio:1576 sci.med:7692 Path: utzoo!utgpu!watmath!clyde!att!ihlpa!krista From: krista@ihlpa.ATT.COM (Anderson) Newsgroups: sci.bio,sci.med Subject: Blood Questions Message-ID: <10241@ihlpa.ATT.COM> Date: 2 Nov 88 19:02:18 GMT Organization: AT&T Bell Laboratories - Naperville, Illinois Lines: 28 <> I have two blood questions: 1. In my parents' family of 5 children, 3 are Rh positive, 1 is Rh negative, and 1 says he used to be positive, but now is tested as negative. I don't think it's possible to change Rh factor, is it? 2. I read in _Encyclopedia_Britannica_ that the A factor helps give immunity against smallpox and the B factor helps protect from certain kinds of cancer. Since I've read about Native Americans and ethnology, I'm surprised I've never heard this before. Incidence of types A and B is very low among Native Americans, and by 1700, 80-90% of Native Americans had died of various European diseases, esp. smallpox. The encyclopedia went on to say that the Blackfeet tribe had about 59% type A at the time that it was measured. The authors hypothesize that a smallpox epidemic devastated the majority of people with O type. I have read from other sources that this tribe has a high incidence of type A, unlike any other American tribe. My question is, has anyone else read about type A to smallpox correlation? One doesn't usually doubt the _Encyclopedia_Britanica_! If anyone is in the know, it would be interesting to see the relationships of blood factors to phenotypic expressions. Thanks in advance. Krista A.