Path: utzoo!utgpu!watmath!uunet!bionet!nihcu.bitnet!CZJ From: CZJ@nihcu.bitnet Newsgroups: bionet.sci-resources Subject: (none) Message-ID: <8812101431.AA02521@net.bio.net> Date: 10 Dec 88 14:19:36 GMT Sender: daemon@NET.BIO.NET Lines: 276 Attached is the Table of Contents and Items of Interest from the NIH Guide to Grants and Contracts dated 12/09/88. Jim Cassatt -------------------- Vol. 17, No. 41, December 9, 1988 DATED ANNOUNCEMENTS (RFPs AND RFAs) FUNCTIONAL NEUROMUSCULAR STIMULATION FOR RESTORATION OF HAND GRASP (RFP) .........................................(84/119)............... 1 National Institute of Neurological Disorders and Stroke Index: NEUROLOGICAL DISORDERS AND STROKE COMMUNITY PROGRAMS FOR CLINICAL RESEARCH ON AIDS (RFP) .....(122/227)....... 1 National Institute of Allergy and Infectious Diseases Index: ALLERGY AND INFECTIOUS DISEASES ONGOING PROGRAM ANNOUNCEMENTS NATIONAL RESEARCH SERVICE AWARDS FOR INSTITUTIONAL RESEARCH TRAINING GRANTS IN ACQUIRED HUMAN IMMUNODEFICIENCY VIRUS (HIV) SYNDROME .............................................(241/285)....... 3 National Institute of Mental Health National Institute on Alcohol Abuse and Alcoholism Index: MENTAL HEALTH, ALCOHOL ABUSE AND ALCOHOLISM NATIONAL RESEARCH SERVICE AWARDS FOR RESEARCH TRAINING FOR INDIVIDUAL FELLOWS IN ACQUIRED HUMAN IMMUNODEFICIENCY (HIV) SYNDROME .............................................(288/338)....... 3 National Institute of Mental Health National Institute on Alcohol Abuse and Alcoholism Index: MENTAL HEALTH, ALCOHOL ABUSE AND ALCOHOLISM BIOMEDICAL RESEARCH SUPPORT SHARED INSTRUMENTATION GRANTS ..(341/532)....... 4 Division of Research Resources Index: RESEARCH RESOURCES RESEARCH CAREER AWARDS IN THROMBOSIS .......................(535/792)....... 6 National Heart, Lung, and Blood Institute Index: HEART, LUNG, AND BLOOD PATIENT OUTCOME ASSESSMENT RESEARCH PROGRAM ASSESSMENT TEAMS ..(795/1062)...10 National Center for Health Services Research and Health Care Technology Index: HEALTH SERVICES RESEARCH, HEALTH CARE TECHNOLOGY BIOMEDICAL RESEARCH SUPPORT SHARED INSTRUMENTATION GRANTS P.T. 36; K.W. 0735000 Division of Research Resources Application Receipt Date: March 31, 1989 BACKGROUND The Division of Research Resources (DRR) is continuing its competitive Biomedical Research Support (BRS) Shared Instrumentation Grant (SIG) Program initiated in Fiscal Year 1982. The program was established in recognition of the long-standing need in the biomedical research community to cope with rapid technological advances in instrumentation and the rapid rate of obsolescence of existing equipment. The objective of the program is to make available, to institutions with a high concentration of PHS-supported biomedical investigators, research instruments which can only be justified on a shared-use basis and for which meritorious research projects are described. An eligible institution may submit more than one application for different instrumentation for the March 31, 1989, deadline. However, if multiple applications are submitted for similar instrumentation from one or more eligible components of an institution, then documentation from a high administrative official must be provided, stating that the multiple applications are a coordinated institutional resource plan, not an unintended duplication. RESEARCH GOALS AND SCOPE This program is designed to meet the special problem of acquisition and updating of expensive shared-use instruments which are not generally available through other PHS mechanisms, such as the regular research project, program project and center grant programs, the Biomedical Research Technology Grant Program, or the Biomedical Research Support (BRS) Grant Program. Proposals for the development of new instrumentation will not be considered. ELIGIBILITY The BRS Shared Instrumentation Grant Program is a subprogram of the BRS Grant Program of DRR. Awards are made under the authority of the BRS program and are made to institutions only, not to individuals. Therefore, eligibility is limited to institutions which receive a BRS grant award. Awards are contingent on the availability of funds. MECHANISM OF SUPPORT BRS Shared Instrumentation Grants provide support for expensive state-of-the-art instruments utilized in both basic and clinical research. Applications are limited to instruments that cost at least $100,000 per instrument or system. The maximum award is $400,000. Types of instrumentation supported include, but are not limited to, nuclear magnetic resonance systems, electron microscopes, mass spectrometers, protein sequencer/amino acid analyzers and cell sorters. Support will not be provided for general purpose equipment or purely instructional equipment. Proposals for "stand alone" computer systems will only be considered if the instrument is solely dedicated to the research needs of a broad community of PHS-supported investigators. Vol. 17, No. 41, December 9, 1988 - Page 4 Awards will be made for the direct costs of the acquisition of new, or the updating of existing, research instruments. The institution must meet those costs (not covered in the normal purchase price) required to place the instrumentation in operational order as well as the maintenance, support personnel and service costs associated with maximum utilization of the instrument. There is no upper limit on the cost of the instrument, but the maximum award is $400,000. Grants will be awarded for a period of one year and are not renewable. Supplemental applications will not be accepted. The program does not provide indirect costs or support for construction or alterations and renovations. Cost sharing is not required. If the amount of funds requested does not cover the total cost of the instrument, the application should describe the proposed source(s) of funding for the balance of the cost of the instrument. Documentation of the availability of the remainder of the funding, signed by an appropriate institutional official, must be presented to DRR prior to the issuance of an award. A major user group of three or more investigators should be identified. A minimum of three major users must have PHS peer-reviewed research support at the time of the award. The application must show a clear need for the instrumentation by projects supported by multiple PHS research awards and demonstrate that these projects will require at least 75 percent of the total usage of the instrument. Major users can be individual researchers, or a group of investigators within the same department or from several departments at the applicant institution. PHS extramural awardees from other institutions may also be included. If the major user group does not require total usage of the instrument, access to the instrument can be made available to other users upon the advice of the internal advisory committee. These users need not be PHS awardees, but priority should be given to PHS-supported scientists engaged in biomedical research. ADMINISTRATIVE ARRANGEMENTS Each applicant institution must propose a Principal Investigator who can assume administrative/scientific oversight responsibility for the instrumentation requested. An internal advisory committee to assist in this responsibility should also be utilized. The Principal Investigator and the advisory group are responsible for the development of guidelines for shared use of the instrument, for preparation of all reports required by the NIH, for relocation of the instrument within the grantee institution if the major user group is significantly altered and for continued support for the maximum utilization and maintenance of the instrument in the post-award period. A plan should be proposed for the day-to-day management of the instrument including designation of a qualified individual to supervise the operation of the instrument and to provide technical expertise to the users. Specific plans for sharing arrangements and for monitoring the use of the instrument should be described. If a grant award is made, a final progress report will be required which describes the use of the instrument, listing all users, and indicating the value of the instrumentation to the research of the major users and to the institution as a whole. This report is due within 90 days following the end of the project period. REVIEW PROCEDURES AND CRITERIA Applications are reviewed by specially convened initial review groups of the Division of Research Grants (DRG) for scientific and technical merit and for program considerations by the National Advisory Research Resources Council (NARRC) of the DRR. Approximately half of the applications will be reviewed at the September 1989 NARRC meeting and the remainder at the NARRC meeting in February 1990. Funding decisions on all applications received for the March 31, 1989 deadline will not be made until the program receives an appropriation for FY 1990. The Council date will not effect funding decisions. Criteria for review of applications include the following: o The extent to which an award for the specific instrument would meet the scientific needs and enhance the planned research endeavors of the major users by providing an instrument that is unavailable or to which availability is highly limited. o The availability and commitment of the appropriate technical expertise within the major user group or the institution for use of the instrumentation. Vol. 17, No. 41, December 9, 1988 - Page 5 o The adequacy of the organizational plan and the internal advisory committee for administration of the grant including sharing arrangements for use of the instrument. o The institution's commitment for continued support of the utilization and maintenance of the instrument. o The benefit of the proposed instrument to the overall research community it will serve. METHOD OF APPLYING Copies of a more detailed announcement are being mailed to Program Directors of BRS grants and to sponsored program offices at all institutions currently receiving BRS grants. Interested investigators should obtain the complete announcement prior to preparing an application. Applications must be received by March 31, 1989. Applications received after this date will not be accepted for review in this competition. The original and four copies should be sent to: Application Receipt Office Division of Research Grants National Institutes of Health Westwood Building, Room 240 Bethesda, Maryland 20892** If appendix material is submitted, four collated sets must be included with the application package. Identify each of the four sets with the name of the principal investigator and the project title. This material will not be routinely duplicated and will be used in a limited way by members of the initial review group. Two copies of the application and one copy of any appendix material should be addressed to: Biomedical Research Support Program Division of Research Resources National Institutes of Health Westwood Building, Room 10A06 5333 Westbard Avenue Bethesda, Maryland 20892 Inquiries should be directed to the Biomedical Research Support Program Office at (301) 496-6743. This program is described in the Catalog of Federal Domestic Assistance number 13.337, Biomedical Research Support. Awards will be made under the authority of the Public Health Service Act, Section 301 (Public Law 78-410, as amended; 42 USC 241) and administered under PHS grant policies and Federal Regulations 42 CFR Part 52 and 45 CFR Part 74. This program is not subject to A-95 Clearinghouse or Health Systems Agency Review.