Xref: utzoo sci.bio:1690 sci.med:8208 Path: utzoo!utgpu!watmath!clyde!att!osu-cis!tut.cis.ohio-state.edu!bloom-beacon!bu-cs!purdue!decwrl!sun!pitstop!sundc!seismo!uunet!portal!cup.portal.com!mmm From: mmm@cup.portal.com (Mark Robert Thorson) Newsgroups: sci.bio,sci.med Subject: Neoteny and Human Genetic Engineering Message-ID: <13127@cup.portal.com> Date: 2 Jan 89 21:15:04 GMT Organization: The Portal System (TM) Lines: 31 At the end of Stephen Jay Gould's book Mismeasure of Man, there is a short epilogue regarding his belief that man is a neotenous form of an ape-like ancestor. Neoteny refers to juvenile characteristics. For decades, some scientists have noticed that some animals appear like neotenous versions of other animals. For example, the head of an adult spaniel appears similar to the head of a terrier puppy. The illustration in Gould's book shows the human-like shape of a baby chimp's head. As I recall, there a tremendous amount of common genetic material between ourselves and our closest primate relatives. I forget the exact figure, but only a few percent makes the difference between a man, a gorilla, or a chimpanzee. What if that small amount of difference encodes a clock that decides when to arrest the development of adult features? Wouldn't it be fun to try pushing it forward to get a race of super-geniuses, or pushing it back to see what pre-man must have been like? Of course there would be enormous social problems with trying to do it in this country, but once the Human Genome Project reveals the clock, a technological backwater nation could do it as an exercise and demonstration of their own talent (recall the pioneering work in fetal cell transplants done in Mexico). Another possibility, with lighter ethical baggage, would be to neotenize one of our primate cousins. If its intelligence could be raised by a factor of 10, it could be darn useful as an assistant or for assembly-line work. Imagine that! "Hey Chimpman, change the channel." "Chimpman, bring me a beer." "Chimpman, grade this stack of freshman midterm exams."