Path: utzoo!utgpu!watmath!uunet!bionet!bloom-beacon!bu-cs!ncsuvx!mcnc!uvaarpa!hudson!biochsn!wrp From: wrp@biochsn.acc.virginia.edu (William R. Pearson) Newsgroups: bionet.molbio.genbank Subject: Re: lostmail on translated databases? Message-ID: <980@hudson.acc.virginia.edu> Date: 8 Jan 89 20:23:48 GMT References: <12460917770.15.VCORCES.BISHOP@BIONET-20.BIO.NET> Sender: news@hudson.acc.virginia.edu Reply-To: wrp@biochsn.acc.Virginia.EDU (William R. Pearson) Organization: University of Virginia, Charlottesville Lines: 16 > Seems that people are in need of the translated database searching >capability mentioned here in this bb by James Fickett and others a while back. One of the standard parts of the FASTA sequence search package (Pearson and Lipman, PNAS (1988) 85:2444) is a program called TFASTA, which compares a protein sequence to a DNA sequence (or library of sequences) by translating the DNA sequence in all six frames. The FASTA package is available for downloading to UNIX computers over the arpanet from the host uvaarpa (ftp uvaarpa, login as anonymous, get the file public_access/fasta.shar) or on floppy disks for the IBM-PC and the Macintosh for $60.00 prepaid, $85.00 P/O, with complete source code. Send checks to: William R. Pearson 1611 Westwood Rd. Charlottesville, VA 22901