Path: utzoo!utgpu!watmath!uunet!bionet!bilbo.bio.purdue.edu!smithj%ewald.decnet From: smithj%ewald.decnet@BILBO.BIO.PURDUE.EDU ("EWALD::SMITHJ") Newsgroups: bionet.jobs Subject: POSTDOCTORAL POSITION AVAILABLE Message-ID: <8901240011.AA12683@net.bio.net> Date: 24 Jan 89 00:09:00 GMT Sender: daemon@NET.BIO.NET Lines: 24 Postdoctoral position A postdoctoral position is available in an X-ray crystallography laboratory to work on the determination of the three-dimensional structure of glutamine PRPP amidotransferase. The project has components of both crystallography and molecular biology. Crystals of diffraction quality have recently been obtained and the structure analysis is underway. Design and production of site-directed mutants and improvements to an existing expression system are needed for future structural studies. Candidates with crystallographic experience and an interest in molecular biology are preferred, although those with a solid background in biochemistry and a strong interest in molecular structure will be considered. The crystallography laboratory is well equipped with an area- detector diffractometer, rotating anode X-ray generators, X-ray cameras, molecular graphics workstations, film scanning facility and an excellent local computing and supercomputing environment. The molecular biology laboratory is fully equipped and includes access to facilities for oligonucleotide synthesis and protein sequencing. Candidates should send a curriculum vitae and names and addresses of at least two references. Contact: Dr. Janet L. Smith, Dept. of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA, (317)494-9246, SMITHJ@EWALD.BIO.PURDUE.EDU (internet), SMITHJ@PURCCVM (bitnet), or Dr. Howard Zalkin, Dept. of Biochemistry, Purdue University, West Lafayette, IN 47907, USA, (317)494-1618.