Path: utzoo!attcan!uunet!bionet!bionet-20.bio.net!CABELL.ANDREWS From: CABELL.ANDREWS@BIONET-20.BIO.NET (Paul Andrews) Newsgroups: bionet.jobs Subject: Permanent position Message-ID: <12469108608.22.CABELL.ANDREWS@BIONET-20.BIO.NET> Date: 8 Feb 89 20:59:18 GMT Sender: daemon@NET.BIO.NET Lines: 174 Organic Analytical Chemist: I am just about finished my post-doctoral work here in Creed Abell's lab at the University of Texas at Austin and I am seeking a PERMANENT position. I have extensive experience in all type of HPLC (normal phase, reverse phase,ion exchange, GPC, peptides, proteins) as well as mass spectrometry (FAB, DCI, DEI, FD, LC-MS, GC-MS) as well as some synthetic work. In addition, I am responsible for telecommunications in our lab and I am quite familiar with the IntelliGenetics suite of programs. Please respond to the address given below or E-MAIL (ARPANET) to: CABELL.ANDREWS@BIONET-20.BIO.NET Thanks, Paul Andrews, PhD. ############################################################################ RESUME FOR PAUL ANDREWS PERSONAL DATA: Address: 610A Genard St; Austin, Texas, USA, 78751 Birthdate: June 16,1954 Citizenship: Canadian Marital Status:Married Phone: Home: (512) 323-5972, Work: (512) 471-3659, 471-1731 E-Mail (ARPANET):CABELL.ANDREWS@BIONET-20.BIO.NET EDUCATIONAL DATA: UNIVERSITY: PhD.,Chemistry, McMaster University, Hamilton, Ontario, Canada, August, 1987. MSc., Analytical Toxicology, Queen's University, Kingston, Ontario, Canada, June, 1981. BSc., Chemistry, McMaster University, Hamilton, Ontario, Canada, May, 1978. SECONDARY: Oakville Trafalgar Secondary School, Oakville, Ontario. HONOURS AND AWARDS: 1973: Ontario Scholar 1978: Queen's Graduate Fellowship WORK EXPERIENCE: Aug.1987-Aug. 1989: Post Doctoral Research Fellow, University of Texas, Austin, Texas, USA. Jan.-Apr. 1986: Lecturer, Mohawk College, Hamilton, Ontario, Canada May-Aug. 1977-1978: Summer research assistant, McMaster University Aug. 1972-1984: Games operator, Canada's Conklin Shows, Toronto, Ontario. Jan.-July 1974: Greenstacker operator, British Columbia Forest Products, McKenzie, British Columbia. May-Aug. 1973: Ford Motor Co., Oakville, Ontario Sept.-Dec.1973: Borg-Warner Co.,Ltd., Oakville, Ontario. REFERENCES 1. Dr. Creed Abell, PhD., Henry M. Burlage Endowed Centennial Professor, College of Pharmacy, Division of Medicinal Chemistry, University of Texas at Austin, Austin, Tx, USA, Zip:78712, Phone: (512) 471-5715. 2. Dr.Dennis McCalla, PhD., Vice President Health Sciences, Health Science Center, Rm 2E1, McMaster University, Hamilton, Ontario, Canada, Code:L8N 3Z5, Phone:(416) 525-9104. 3. Dr. Mike A. Quilliam,PhD., Senior Research Scientist, Atlantic Research Laboratory, National Research Council, 1411 Oxford St, Halifax, Nova Scotia, B3H 3Z1, (902) 426-9736. INTERESTS Member Canadian Amateur Swimming Association Member American Swimming Association Bicycling Reading ------------------------------------------------------------------------------ PROFFESIONAL ESSAY Throughout my research career, I have tried to become proficient in the area of organic analytical chemistry with emphasis on trace analysis by HPLC and mass spectrometry. In addition I also also wished to develop computer skills for acquisition and manipulation of experimental data. I specialized in analytical courses when obtaining an undergraduate degree in chemistry. As an undergraduate summer research assistant I developed methods for determining isotope incorporation by mass spectrometry gas phase analysis of PCBs by gas chromatography. My MSc. analytical chemistry courses at Queen's University allowed me to obtain hands on experience in many inorganic analytical methods such as AA, XRF, polarography,and ASV, as well as organic analytical methods such as GC, HPLC and GC-MS. I also learned techniques in animal surgery, toxicology, biochemistry, and analytical problems associated with analysis of biological matrices. My MSc. work research involved the development of new extraction and derivatization methods for the GC and GC-MS analysis of alkaloids from a biological matrix. My PhD courses at McMaster University addressed problems in applied toxicology and developing approaches to solving non-routine problems such as the analysis of PAHs in oil sands. My PhD research dealt with the isolation and characterization of adducts formed between DNA and nitrated aromatic hydrocarbons. I extensively investigated methods for the gentle derivatization and ionization of these nonvolatile, polar compounds by mass spectrometry. Some the techniques used were EI, CI, FAB, GC-MS, LC-MS, and FD. During this work I gained expertise in in the handling and synthesis of radioactive compounds, and the use of bacteria as markers of toxicity. Most of the research involved the use of state of the art HPLC for multi wavelength detection of metabolites and DNA-adducts. As most of the equipment was controlled by computer systems, I learned to acquire and manipulate data by computers as well as learning computer languages such as BASIC and FORTRAN. My post-doctoral research centers on HPLC and mass spectrometric (probe and GC-MS) characterization of proteins, peptides, and riboflavin analogues. I set up and manage a Beckman System Gold HPLC system which is responsible for the computer control of a number of other HPLC systems used in our laboratory. I also developed software for the graphical analysis of data obtained from these HPLCs and am presently teaching myself C, a programming language. I am acquainted with telecommunications and network protocols because I am responsible for maintaining computer communications to BIONET, a molecular biology computer facility in California. I make extensive use of the Intelligenetics Suite of programs on BIONET, and electronic bulletin board facilities to make contact with other researchers all over the world. I have also helped in the drafting of several major research grant proposals. My experiences in various laboratories has allowed me to gain wide experience in the area of HPLC and mass spectrometry, especially in area of toxicology. Yet, by developing skills in solving problems in many areas of organic analytical chemistry I hope to be an asset to a firm interested in someone who can deal with situations that call for a wide range of problem solving abilities. My ability to manage people and to delegate responsibility would also aid me in a mangerial position. PUBLICATIONS Papers in Refereed Journals. 1. N.H. Werstiuk and Paul Andrews. "Base-catalysed hydrogen isotope exchange of thiocamphor:alpha-thioenolization rate constants", Canadian Journal of Chemistry, 56, 2605-2606, (1978). 2. F. Messier, C. Lu., P. Andrews, B. McCarry,D. Bryant, and D. McCalla. "The metabolism of 1-nitropyrene and formation of DNA adducts in Salmonella typhimurium". Carcinogenesis, 2, 1007-1011, (1981). 3. M. Quilliam, F. Messier, C. Lu, P. Andrews, B. McCarry and D. McCalla, "The metabolism of nitro-substituted polycyclic aromatic hydrocarbons in Salmonella typhimurium", in: Polynuclear Aromatic Hydrocarbons :Physical and biological Chemistry., ed. M. Cook, A. Dennis and G. Fisher, Battelle Press, pp 667-672 (1982). 4. P. Andrews, D. Bryant, S. Vitakunes, M. Gouin, G. Anderson, B. McCarry, M. Quilliam and D. McCalla, "Metabolism of nitro-polycyclic aromatic hydrocarbons and formation of DNA adducts in Salmonella typhimurium", in :Polynuclear Aromatic Hydrocarbons:Formation, Metabolism and Measurement, ed M. Cooke and A. Dennis, Battelle Press, pp 89-98, (1983). 5. P. Andrews, J. Brien, C. Loomis and J. Page, "Gas chromatographic determination of salsolinol in the striatum of the rat", Canadian Journal of Physiology and Pharmacology, 6. P. Andrews, M. Quilliam, B. McCarry, D. Bryant, and D. McCalla, "Indentification of the DNA adduct formed by the metabolism of 1,8- dinitropyrene in Salamonella typhimurium", Carcingenesis, 7, 105-110, (1986). 7. P. Andrews, J. Orr, I. Lambert, D. Bryant, L. Davidson, B.. McCarry, and D. McCalla, "The fate of 1,8-dinitropyrene in Salmonella typhimurium:Metabolism and DNA adduct formation" in Polynuclear Aromatic Hydrocarbons, ed M. Cooke, Battelle Press, (1986). 8. I. Lambert, P. andrews, L. Davidson, D. Bryant, and D. McCalla, "The detection of dinitropyrene adducts in DNA", Environmental Mutation Society, 8, Supp. 6, 43, (1986). CONTRIBUTED CONFERENCE PAPERS 1. D.McCalla, B. McCarry, M. Quilliam, P. Andrews, and C. Lu,"Mutagenicity of nitropyrenes in Salmonella typhuimurium: Activation by endogenous reductases and formation of DNA adducts", 13th International Cancer Congress, Seattle, (1982). 2. D. McCalla, M. Quilliam, B. McCarry, C. Lu, F. Messier and P. Andrews, "Metabolism of nitropyrenes and formation of DNA adducts in Salmonella typhimurium" 5th CIIT Conference on toxicology, The Chemical Industry Institute of Toxicology, Raleigh, NC, (1982). -------