Xref: utzoo sci.research:682 talk.politics.misc:22587 sci.bio:1873 soc.culture.jewish:9621 Path: utzoo!utgpu!jarvis.csri.toronto.edu!mailrus!tut.cis.ohio-state.edu!ucbvax!decwrl!sun!pitstop!sundc!seismo!uunet!portal!cup.portal.com!hkhenson From: hkhenson@cup.portal.com (H Keith Henson) Newsgroups: sci.research,talk.politics.misc,sci.bio,soc.culture.jewish Subject: Re: The Ubiquity of Tay-Sachs: a shocking but elegant theory Message-ID: <15018@cup.portal.com> Date: 24 Feb 89 08:36:23 GMT References: <10276@ut-emx.uucp> Organization: The Portal System (TM) Lines: 11 In a privious posting Eric S. Raymond writes of the possibility that plague might have a selective effect on the incidence of Tay-Sachs. Maybe, but if my memory of plague is correct, it has only intermittantly broken out among the rodent populations, with hundreds of years between episodes. This is quite unlike the pressure that malaria puts on human gene selection. An alternate way the gene could have become widespread is that a lot of people are desended from someone in which the mutation occured. When a people moves into a relatively unpopulated area, that happens. Keith Henson hkhenson@cup.portal.com