Xref: utzoo sci.med:8950 sci.physics:6080 sci.electronics:5316 Path: utzoo!utgpu!jarvis.csri.toronto.edu!mailrus!tut.cis.ohio-state.edu!rutgers!bpa!manta!conrad!sac From: sac@conrad.UUCP (Steven A. Conrad) Newsgroups: sci.med,sci.physics,sci.electronics Subject: Re: Biomedical Measurement "Challenge": Cardiac Output Keywords: biomedical measurements, cardiac output, instrumentation Message-ID: <157@conrad.UUCP> Date: 23 Feb 89 01:52:30 GMT References: <13175@steinmetz.ge.com> <156@conrad.UUCP> Reply-To: sac@conrad.UUCP (Steven A. Conrad) Distribution: usa Organization: Louisiana State University Medical Center, Shreveport Lines: 22 In my previously submitted article, I neglected to mention a method which has recently hit the market, thoracic bioimpedance. The method involves running a constant current through the chest by means of electrodes placed at the neck and base of the thorax, and measuring voltage changes. A sufficiently high frequency is used so as not to intefere with biological function. Equations have been worked out for relating the rate of change of impedence with each stroke of the heart to the volume ejected by the heart (stroke volume). Multiply this by heart rate and you have cardiac output. We have evaluated this instrument and found it to be of sufficient accuracy for clinical uses. It perhaps best supplements, not replaces the pulmonary artery catheter, since the catheter has other important functions. Several investigators have reported reasonable correlations with thermodilution. Steve -- Steven A. Conrad, Department of Medicine (Critical Care) Louisiana State University Medical Center, Shreveport, LA UUCP: sac@conrad.UUCP, Internet: conrad@manta.pha.pa.us "Silence is the only successful substitute for brains"