Path: utzoo!utgpu!watmath!iuvax!bionet!sysh.surrey.ac.uk!MBY134
From: MBY134@sysh.surrey.ac.uk
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Date: 13 Mar 89 17:39:21 GMT
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        Post Doctoral Molecular Biologist required in The Molecular
        Microbiology Group, Department of Microbiology, University of
        Surrey, Guildford, Surrey, UK.

        The position is funded for two years from 1 April 1989, by the
        National Foundation for Ileitis and Colitis of America and is to
        develop the polymerase chain reaction for detection of
        mycobacterial DNA in Crohn's disease. Crohn's disease is a
        chronic incurable intestinal inflammatory condition that affects
        approximately 50 000 people in the UK and many more in the USA.
        The cause is unknown though mycobacteria, particularly
        Mycobacterium paratuberculosis have been implicated. We have
        developed DNA probes for specific detection of mycobacteria
        (McFadden et al 1987. J. Clin. Microbiol. 25: 796 - 801; McFadden
        et al 1987. Mol. Microbiol. 1: 283 - 291). DNA sequence
        determined from these probes will be used to synthesize specific
        primers for enzymic amplification of mycobacterial DNA in samples
        derived from Crohn's disease sample and cultures. The association
        of mycobacteria with Crohn's disease will be determined. Rapid
        detection of mycobacteria in patient samples will allow specific
        targeted treatment and hopefully, cure of this disease.

        Starting salary will be up to #14033 per annum. Applications in
        the form of a curriculum vitae (3 copies), including the names
        and adresses of two referees, should be sent to the Personnel
        Office (JLG), University of Surrey, Guildford, Surrey, GU2 5XH,
        UK, by 24 March 1989 quoting reference 816. Further details can
        be obtained from Dr. JJ McFadden (0483 571281 ext 2671).