Path: utzoo!attcan!uunet!bionet!ibm.sheffield.ac.uk!BI1JK From: BI1JK@ibm.sheffield.ac.uk Newsgroups: bionet.software Subject: (none) Message-ID: <23.Apr.89.17:16:49.BST.#0293@UK.AC.SHEF.IBM> Date: 23 Apr 89 16:16:36 GMT Sender: daemon@NET.BIO.NET Lines: 80 THE PROGRAM, EZ-FIT, FOR THE IBM PC HAS BEEN ADDED TO THE UK PUBLIC SOFTWARE SYSTEM AT LANCASTER.PD-SOFTWARE. IT IS A BOO ENCODED ARC FILE WHICH MAY BE UNPACKED USING TOOLS AVAILABLE ON THE SAME LIBRARY SYSTEM. THE FILE IS IN THE DIRECTORY 'MICROS/IBMPC/G49' AND IS CALLED: g49ezfit.boo A BOO-encoded ARC file Tools Needed ------------ DEBOO.EXE PKUNPAK.EXE Written By ---------- F.W.Perella Date Mounted or Updated ----------------------- 14/04/89 Description ----------- Ez-fit is a program which may be used to fit ENZYME KINETIC DATA. It fits experimental data to a user-selected model, chosen from a wide array of kinetic models and presents the fitted data in both tabular and graphic forms (CGA type graphics appear on an EGA monitor) The program is binary executable (compiled Quick Basic) and needs at least 384 Kbytes of RAM and a CGA Graphics adaptor. The program and description have been published: F.W. Perella (1989) "EZ-FIT: A Practical Curve Fitting Microcomputer Program for the Analysis of Enzyme Kinetic Data on IBM-PC Compatible Computers" Anal. Biochem., 174: 437 - 447. WITH CONSIDERABLE DIFFICULTY, AFTER TRYING TO USE THE FTP SYSTEM, WE HAD JOE SMITH AT U. PENN. SEND IT AS A UU-ENCODED FILE, SPLIT INTO 5 PARTS, USING THE MAIL NETWORK. I HAVE DECODED, UNPACKED THE FILE, AND RE- PACKAGED IT USING PKPAK. IT NOW WORKS. IT WOULD BE MUCH EASIER MAKING IT AVAILABLE HERE AND I HAVE ASKED THEIR PERMISSION TO DO SO. THE PROGRAM HAS BEEN MADE AVAILABLE (BY ANONYMOUS FTP) VIA INTERNET FROM THE DEPARTMENT OF BIOCHEMISTRY & BIOPHYSICS, UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA - NEWS MESSAGE VIA DARESBURY ON 28TH FEBRUARY ON "BIONET- PC-SOFTWARE-ARPANET". JOE SMITH IN HIS MESSAGE (ON NEWS%EDU.UPENN. DCCS.SCOTTY @NET.BIO.NET) STATES THAT THE PROGRAM IS BEING MADE AVAILABLE TO THE ACADEMIC COMMUNITY WITH THE PERMISSION OF THE AUTHOR, AND THAT WE SHOULD "FEEL FREE TO SHARE EZ-FIT WITH YOUR COLLEAGUES" ALL REQUESTS FOR INFORMATION CONCERNING THE USE OF THE PROGRAM, OR COMMENTS SHOULD, OF COURSE, BE SENT TO DR PERELLA. I WOULD BE HAPPY TO >> act as a postbox for sending such comments on by 'e-mail' to U. Penn. >> and hence to the author. Dr. Perrella is very interested in improving >> the package and keeping it available to the public." >> >> It seems to be an extremely good package which would be enormously >> useful to almost every Biochemistry, Microbiology, Genetics, Chemistry >> (?), Molecular Biology Department in the UK. >> >> Julian Kinderlerer >> Department of Molecular Biology & Biotechnology, >> Biochemistry Section, >> The University, >> Sheffield >> S10 2TN >> (0742) 768555 ext 4324 >> (Bi1jk@shef.pa or bi1jk@shef.ibm) Notes ----- To obtain the programs, download the BOO-encoded file or files, and use the DeBOO utility to turn each one into a .ARC file. You can then use the PKUNPAK utility to unpack the individual files. THESE UTILITIES ARE IN MICROS/IBMPC/H99 AT LANCASTER.PD-SOFTWARE